Another good point for the Pfizer / BioNTech vaccine? The two companies claimed on April 1 that their vaccine retained very high efficacy against the South African variant of the coronavirus, citing findings from clinical trials in South Africa.
No cases of covid in vaccinees
According to these companies, no cases of covid-19 have been observed in South Africa – where the South African variant circulates widely – in people vaccinated in a phase 3 trial. For up to six months. after their second injection, according to a statement.
In this country, “800 participants were recruited, nine cases of covid-19 were observed, all in the placebo group (unvaccinated group, editor’s note), which indicates a vaccine efficacy of 100%“, explains the Pfizer / BioNTech alliance.
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“End this pandemic”
It’s about “early clinical results showing that a vaccine can effectively protect against variants currently in circulation, a key factor in achieving group immunity and ending this pandemic for the global population“, welcomes Ugur Sahin, CEO and co-founder of BioNTech, in the press release.
Pfizer and BioNTech had already estimated in January, from tests carried out in vitro, that even if it was “lower“to the response observed against the old strain of the virus,”high efficiency“against the South African variant did not appear to be affected. Data from clinical trials seem to corroborate these new findings.
Over 91% efficiency
In total, out of all 46,307 participants in phase 3 trials conducted in several countries where different variants of the virus circulate, the Pfizer / BioNTech vaccine has demonstrated an efficacy of 91.3%, again according to the two companies.
Of the 927 symptomatic cases of covid-19 in the study, 850 cases were in patients in the unvaccinated placebo group and 77 cases were in the vaccinated group.
Are these results to be taken with caution? Indeed, all of these data have not yet been published in scientific journals and have therefore not been validated by independent scientists.